Posted October 30, 2008on:
Chromosome 11, Partial Trisomy 11q
It is possible that the main title of the report Chromosome 11, Partial Trisomy 11q is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- 11q Partial Trisomy
- Chromosome 11, Partial Trisomy 11q13-qter
- Chromosome 11, Partial Trisomy 11q21-qter
- Chromosome 11, Partial Trisomy 11q23-qter
- Distal Trisomy 11q
- Partial Trisomy 11q
- Trisomy 11q, Partial
Chromosome 11, Partial Trisomy 11q is a rare chromosomal disorder in which the end (distal) portion of the long arm (q) of the 11th chromosome appears three times (trisomy) rather than twice in cells of the body. Although associated symptoms and findings may vary, the disorder is often associated with delayed growth before and after birth (prenatal and postnatal growth retardation); varying degrees of mental retardation; distinctive abnormalities of the skull and facial (craniofacial) region; and/or other features. Chromosomal analysis is necessary for a definite diagnosis..
ResourcesChildren’s Craniofacial Association
13140 Coit Road
Dallas, TX 75240
Support Organization for Trisomy 18, 13, and Related Disorders
2982 South Union Street
Rochester, NY 14624-1926
March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
The Arc (a national organization on mental retardation)
1010 Wayne Ave
Silver Spring, MD 20910
PO Box 158
South Beloit, IL 61080
American Heart Association
7272 Greenville Avenue
Dallas, TX 75231-4596
P.O. Box 2189
Surrey, Intl CR3 5GN
Tel: 44 0 1883 330766
Fax: 44 0 1883 330766
Craniofacial Foundation of America
975 East Third Street
Chattanooga, TN 37403
Congenital Heart Disease Resource Page
Web Site on the Internet
What is chromosome 11?Chromosome 11 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 11 spans about 134 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 11 likely contains between 1,300 and 1,700 genes.
Genes on chromosome 11 are among the estimated 20,000 to 25,000 total genes in the human genome.
There are many conditions related to genes on chromosome 11.
Is there a standard way to diagram chromosome 11?Geneticists use diagrams called ideograms as a standard representation for chromosomes. Ideograms show a chromosome’s relative size and its banding pattern. A banding pattern is the characteristic pattern of dark and light bands that appears when a chromosome is stained with a chemical solution and then viewed under a microscope. These bands are used to describe the location of genes on each chromosome.
See How do geneticists indicate the location of a gene? in the Handbook. Where can I find additional information about chromosome 11?You may find the following resources about chromosome 11 helpful.
You may also be interested in these resources, which are designed for genetics professionals.
Where can I find general information about chromosomes?The Handbook provides basic information about genetics in clear language.
- What is DNA?
- What is a chromosome?
- How many chromosomes do people have?
- Can changes in chromosomes cause disorders?
These links provide additional genetics resources that may be useful.
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
References (4 links)
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? in the Handbook.