Posted October 30, 2008on:
chromosome 15 trisomy
15 trisomy trisomy 15 trisomy 15 syndrome
Usually a lethal form of chromosomal aberrations. Most surviving infants have mosaic trisomy 15 and exhibit multiple congenital anomalies involving the craniofacial, limb, cardiovascular, and other structures.
Head and neck: Micro/retrognathia.
Ears: Dysmorphic ears.
Nose: Large nose with broad bridge and upturned nares.
Mouth and oral structures: Small mouth, highly arched palate, cleft palate, and narrow lips. Neck: Short and webbed neck.
Thorax: Widely spaced nipples, short sternum, and abnormal number of ribs.
Hand and foot: Overriding fingers and toes, clenched hands, and talipes equinovarus
Cardiovascular system: Heart defects.
Gastrointestinal system: Anteriorly placed anus.
Growth and development: Growth and mental retardation.
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